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Tetsuo Minamino Selected Research

N- (1- ((2,4- diamino- 6- pteridinyl)methyl)- 3,4- dihydro - 2H- 1,4- benzothiazine- 7- carbonyl)- L- 2- aminoadipic acid

4/2004Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts.

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Tetsuo Minamino Research Topics

Disease

27Heart Failure
05/2021 - 03/2002
18Infarction (Infarctions)
12/2017 - 06/2003
17Reperfusion Injury
12/2017 - 06/2003
15Cardiomegaly (Heart Hypertrophy)
09/2016 - 03/2002
13Ischemia
12/2017 - 06/2003
12Neoplasms (Cancer)
10/2021 - 01/2008
12Myocardial Infarction
12/2017 - 06/2003
10Hypertrophy
01/2016 - 03/2002
10Myocardial Ischemia (Ischemic Heart Diseases)
05/2015 - 04/2003
7Fibrosis (Cirrhosis)
10/2021 - 04/2006
7Body Weight (Weight, Body)
10/2008 - 09/2002
4Inflammation (Inflammations)
03/2022 - 04/2006
4Stroke (Strokes)
11/2015 - 05/2012
4Brain Ischemia (Cerebral Ischemia)
11/2015 - 05/2012
3Myocarditis (Carditis)
10/2021 - 01/2016
3Bradycardia
01/2019 - 02/2009
3Hypotension (Low Blood Pressure)
12/2017 - 10/2007
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
11/2015 - 05/2012
3Glucose Intolerance
05/2013 - 04/2006
3Coronary Occlusion
10/2004 - 09/2003
2Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
06/2022 - 07/2021
2Left Ventricular Dysfunction
01/2020 - 07/2006
2Diabetes Mellitus
12/2019 - 05/2013
2Atrial Fibrillation
11/2019 - 01/2019
2Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
01/2019 - 01/2018
2Atherosclerotic Plaque (Atheroma)
11/2018 - 09/2007
2ST Elevation Myocardial Infarction
01/2018 - 10/2012
2Cardiotoxicity
02/2017 - 03/2016
2Hypoxia (Hypoxemia)
02/2015 - 01/2014
2Atherosclerosis
01/2015 - 10/2006
2Breast Neoplasms (Breast Cancer)
07/2014 - 06/2012
2Cardiac Arrhythmias (Arrythmia)
04/2013 - 06/2006
2Cardiovascular Diseases (Cardiovascular Disease)
06/2010 - 04/2006
2Heart Diseases (Heart Disease)
01/2010 - 03/2002
2Ventricular Fibrillation
06/2006 - 01/2005
2Hypertension (High Blood Pressure)
04/2006 - 04/2006

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
02/2017 - 09/2002
10Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2017 - 05/2002
9Pharmaceutical PreparationsIBA
01/2018 - 03/2002
8ErythropoietinFDA Link
01/2018 - 01/2005
8Adenosine (Adenocard)FDA LinkGeneric
05/2015 - 05/2002
7Liposomes (Liposome)IBA
01/2016 - 02/2009
7Adenosine Triphosphate (ATP)IBA
02/2015 - 09/2002
5Phosphotransferases (Kinase)IBA
06/2006 - 09/2002
5NG-Nitroarginine Methyl Ester (L-NAME)IBA
04/2006 - 09/2002
55'-Nucleotidase (5' Nucleotidase)IBA
12/2005 - 09/2003
4Small Interfering RNA (siRNA)IBA
11/2018 - 07/2014
4Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
11/2018 - 06/2012
4Glucose (Dextrose)FDA LinkGeneric
03/2016 - 04/2006
4Neuroprotective AgentsIBA
11/2015 - 05/2012
4Proteasome Endopeptidase Complex (Proteasome)IBA
01/2010 - 02/2006
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
07/2021 - 10/2004
3Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2019 - 09/2002
3Epidermal Growth Factor (EGF)IBA
01/2018 - 06/2012
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2016 - 10/2006
3Purinergic P1 Receptors (Adenosine Receptor)IBA
05/2015 - 10/2003
3Anti-Arrhythmia AgentsIBA
04/2013 - 01/2005
3Atrial Natriuretic Factor (ANF)IBA
10/2007 - 03/2002
3WortmanninIBA
06/2006 - 10/2004
3Hydralazine (Apresoline)FDA LinkGeneric
04/2006 - 09/2002
3Nitric Oxide Synthase (NO Synthase)IBA
04/2006 - 05/2004
3KATP ChannelsIBA
12/2005 - 01/2003
3Protein Kinase CIBA
12/2005 - 07/2004
370-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
04/2003 - 09/2002
2oxidized low density lipoproteinIBA
06/2022 - 07/2021
2SteroidsIBA
10/2021 - 01/2020
2Brain Natriuretic Peptide (Natrecor)FDA Link
01/2020 - 06/2009
2Oxygen (Dioxygen)IBA
01/2019 - 05/2007
2Lipid NanoparticlesIBA
01/2018 - 07/2014
2Proteasome InhibitorsIBA
02/2017 - 04/2009
2Doxorubicin (Adriamycin)FDA LinkGeneric
03/2016 - 06/2012
2Tacrolimus (Prograf)FDA LinkGeneric
01/2016 - 04/2013
2CytokinesIBA
01/2016 - 06/2009
2Messenger RNA (mRNA)IBA
01/2016 - 07/2010
2Dipeptidyl-Peptidase IV InhibitorsIBA
05/2015 - 05/2013
2Glucagon-Like Peptide 1 (GLP 1)IBA
05/2015 - 05/2013
2AMP-Activated Protein KinasesIBA
01/2015 - 05/2009
2Heparin (Liquaemin)FDA LinkGeneric
07/2014 - 06/2012
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2014 - 06/2012
2Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
05/2014 - 04/2013
2Therapeutic UsesIBA
05/2014 - 06/2012
2Adrenergic Receptors (Adrenergic Receptor)IBA
11/2010 - 06/2004
2Histamine (Histamine Dihydrochloride)FDA Link
11/2010 - 05/2006
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2010 - 03/2002
2UbiquitinIBA
01/2010 - 02/2006
2Ubiquitinated ProteinsIBA
04/2009 - 02/2006
2Pravastatin (Pravachol)FDA LinkGeneric
10/2008 - 10/2004
2Nicorandil (SG 75)IBA
10/2007 - 02/2004
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
06/2006 - 10/2004
2Angiotensin IIIBA
04/2006 - 10/2003
2AldosteroneIBA
04/2006 - 07/2005
2Calcium Channel Blockers (Blockers, Calcium Channel)IBA
02/2005 - 04/2003
28-(4-sulfophenyl)theophyllineIBA
10/2004 - 06/2004
2Celiprolol (ST1396)IBA
08/2004 - 04/2003
2Selective Estrogen Receptor Modulators (SERM)IBA
06/2004 - 02/2004
2Raloxifene Hydrochloride (Evista)FDA Link
06/2004 - 02/2004

Therapy/Procedure

18Therapeutics
10/2021 - 02/2004
5Percutaneous Coronary Intervention
01/2018 - 02/2004
5Intravenous Administration
01/2018 - 01/2005
3Intravenous Injections
11/2018 - 05/2014